What happens to blood without platelets after donation?

Wednesday, 19/10/2016

Nowadays, the most widely raised question people usually ask about is regarding donating of blood and how this affects the person. And what does blood consist of, the following willhelp you clear your dilemma.


●Platelets are the cells that circulate in our blood and repairs when they recognise damaged blood vessels.
●The main purpose of platelets is to stop a person from bleeding, so basically platelets function is to clot the blood.
●Platelets contain no cell nucleus in fact they are fragments of cytoplasm that originates from the precursors called megakaryocytes of the bone marrow and then enter the circulation.

2. Low platelet count

●Low platelet count causes a condition called thrombocytopenia. This is caused due to various factors.
●One of the main factor that can cause thrombocytopenia or low platelet count is due to mosquitoes.
●Malaria, Dengue etc. are the diseases which are diagnosed if there is low platelet count.

3. Malaria


●Malaria is usually associated with low platelet count and it’s potentially fatal if not diagnosed and treated early.
●It usually occurs in tropical and subtropical regions of the world.
●Malaria is a blood disease caused by parasites and transmitted through a female mosquito called ‘Anopheles’.
●Basically the bite of this mosquito can be considered fatal as it injects the parasite directly into patient’s bloodstream.
●The parasites injected into a person’s bloodstream goes straight to their liver and starts multiplying before attacking and destroying of red blood cells.


●The acute low platelet count is considered as one of the effective methods of diagnosing of this disease as this protozoan disease results in rapid decrease of the platelets.
●Abnormalities in platelet structure and function have been described as a consequence of malaria, and in some extreme cases platelets can be invaded by malarial parasites.
●The below image abstractly shows the symptoms and statistics of malaria.


4. Dengue


●Another deadly disease caused by mosquitoes is dengue and this is extremely fatal as there is no prevention for this disease.

●Unlike malaria, dengue is a viral disease and is caused by a virus.

●The main cause of dengue fever is the suppression of bone marrow which in turn reduces the production of platelets.
●As bone marrow is the one which manufactures blood cells and suppression of it reduce blood cells and this causes reduction of platelets.
●Studies show that dengue virus can even bind to platelets of human blood in the presence of virus-specific antibody.
●When vascular endothelial cells are infected with this virus it gets combined with platelets and they tend to destroy platelets.
●Sometimes the antibodies that are produce by our body after the infection of dengue can destroy the platelets resulting in low platelet count.

5. Donation of blood

●One of the most crucial question people usually have is what happens to them after donating blood or what happens to their blood
●This section briefly explains what happens to you when you donate blood.
●As soon as you donate blood your blood starts replacing all the cells and fluids you have lost during donation.
●There are cells in kidney called peritubular cells sense that the level of oxygen in our body is reduced which is caused due to loss of red blood cells.
●These cells secrete a protein called erythroprotein which passes through the blood stream until it reaches the bone marrow
●The bone marrow produces stem cells, the building blocks that the body uses to make the different blood cells like red cells, white cells and platelets. The erythropoietin sends a message to the stem cells telling more of them to develop into red blood cells, rather than white cells or platelets.
●And various other proteins like this causes secretion of platelets and white cells.

So, in conclusion it is highly not recommended for some someone with low platelet count to donate blood as there is risk of infection due to this transfusion to other people. And the blood which contains no platelets has no clotting properties and is usually not transferred to other person.